CVE-2024-50636
PyMOL 2.5.0 contains a vulnerability in its "Run Script" function, which allows the execution of arbitrary Python code embedded within .PYM files. Attackers can craft a malicious .PYM file containing a Python reverse shell payload and exploit the function to achieve Remote Command Execution (RCE). This vulnerability arises because PyMOL treats .PYM files as Python scripts without properly validating or restricting the commands within the script, enabling attackers to run unauthorized commands in the context of the user running the application.
Published:Nov 11, 2024
Last Modified:Apr 15, 2026
EPS:Nov 11, 2024
EPSS Score:0.06957
CVSS Score:9.8
Affected Products
Vendor
Product
Action
Vendor
Schrodinger
Product
Pymol
Schrodinger
Pymol
Exploits
No exploit reference
Common Weakness Enumeration
Common Attack Pattern Enumeration and Classification (CAPEC)
Common Vulnerability Scoring System
Attack Vector
Network
Adjacent
Local
Physical
Privileges Required
None
Low
High
User Interaction
None
Required
Scope
Unchanged
Changed
Confidentiality
None
Low
High
Integrity
None
Low
High
Availability
None
Low
High
