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    CVE-2026-31973

    SAMtools is a program for reading, manipulating and writing bioinformatics file formats. Starting in version 1.17, in the cram-size command, used to write information about how well CRAM files are compressed, a check to see if the `cram_decode_compression_header()` was missing. If the function returned an error, this could lead to a NULL pointer dereference. Exploiting this bug causes a NULL pointer dereference. Typically this will cause the program to crash. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

    Published:Mar 18, 2026
    Last Modified:Mar 25, 2026
    EPS:Mar 18, 2026
    EPSS Score:0.00017
    CVSS Score:7.5

    Affected Products

    Vendor
    Samtools
    Product
    Samtools

    Exploits

    No exploit reference

    Common Weakness Enumeration

    CWE-476 NULL Pointer Dereference

    Common Attack Pattern Enumeration and Classification (CAPEC)

    No CAPEC recorded yet

    Common Vulnerability Scoring System

    Attack Vector
    Network
    Adjacent
    Local
    Physical
    Privileges Required
    None
    Low
    High
    User Interaction
    None
    Required
    Scope
    Unchanged
    Changed
    Confidentiality
    None
    Low
    High
    Integrity
    None
    Low
    High
    Availability
    None
    Low
    High